Drew Mestemaker Leads Oklahoma State Past No. 6 Oregon

Drew Mestemaker leads Oklahoma State to 39-31 upset over No. 6 Oregon

Oklahoma State quarterback Drew Mestemaker delivered one of the weekend’s biggest individual performances, leading the Cowboys to a 39-31 upset over No. 6 Oregon on Saturday. Mestemaker threw for 317 yards and two touchdowns, added 109 rushing yards and scored another touchdown on the ground.

The victory ended Oklahoma State’s 21-game losing streak against FBS opponents and gave coach Eric Morris his first win with the program.

Mestemaker’s all-around performance

Mestemaker completed 26 of 43 passes for 317 yards and two touchdowns. He also ran for 109 yards and a score, finishing with 426 total yards and three touchdowns.

His first play from scrimmage set the tone: a 75-yard run that immediately challenged Oregon’s defensive preparation. Later, he delivered a dramatic touchdown run that helped put Oklahoma State in front.

The performance was especially notable because Mestemaker was not widely known primarily for his rushing ability before the game.

Oklahoma State ended a long losing streak

The Cowboys had lost 21 consecutive games against FBS opponents before Saturday’s victory. Defeating a ranked Oregon team therefore represented more than a single upset; it ended a prolonged stretch of difficult results.

Oklahoma State also outgained Oregon 554-281, according to CBS Sports’ game summary.

The win gives the program a major early-season momentum boost and creates national attention around Mestemaker and Morris.

The quarterback duel with Dante Moore

The matchup attracted additional attention because Oregon quarterback Dante Moore was considered a major NFL Draft prospect. Mestemaker outplayed him statistically and controlled important moments of the game.

However, one game should not determine a player’s draft status. Scouts will evaluate film over an entire season, including accuracy, decision-making, pocket movement, processing speed, arm strength and performance against different defensive schemes.

The mistakes that cannot be ignored

Mestemaker threw two interceptions, both described in reports as coming from tipped passes. Those turnovers helped Oregon score 14 points in the first half.

His ability to recover from the mistakes was a major part of the story. A quarterback’s development is not measured only by highlight plays; how he responds after turnovers is equally important.

Is Mestemaker an NFL Draft riser?

The performance could increase interest in Mestemaker as a 2027 NFL Draft prospect. The Athletic described him as outdueling Moore for much of the game, while other coverage suggested his draft stock could rise.

Still, the correct editorial wording is “could raise his profile,” not “he is guaranteed to become a first-round pick.” Draft evaluations change throughout a season.

Bottom line

Drew Mestemaker totaled 426 yards and three touchdowns as Oklahoma State stunned No. 6 Oregon 39-31. The win ended a 21-game FBS losing streak and immediately made Mestemaker one of college football’s most discussed players.